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                        March 18, 2024

       Bo Cumbo
       Chief Executive Officer
       Solid Biosciences Inc.
       500 Rutherford Avenue, Third Floor
       Charlestown, MA 02129

                                                        Re: Solid Biosciences
Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed March 13,
2024
                                                            File No. 333-277871

       Dear Bo Cumbo:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jimmy
McNamara at 202-551-7349 with any questions.




                        Sincerely,


                        Division of Corporation Finance

                        Office of Life Sciences
       cc:                                              Caroline Dotolo