75000 - Document - Document and Entity Information
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75010 - Statement - Consolidated Balance Sheets
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75020 - Statement - Consolidated Balance Sheets (Parenthetical)
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75030 - Statement - Consolidated Statements of Operations
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75040 - Statement - Consolidated Statements of Comprehensive Loss
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75050 - Statement - Consolidated Statements of Changes In Stockholders' Equity
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75060 - Statement - Consolidated Statements of Changes In Stockholders' Equity (Parenthetical)
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75070 - Statement - Consolidated Statements of Cash Flows
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75080 - Statement - Consolidated Statements of Cash Flows (Parenthetical)
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995457 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995467 - Disclosure - Nature of the Business
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995477 - Disclosure - Summary of Significant Accounting Policies
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995487 - Disclosure - Collaborations
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995497 - Disclosure - FA212 Asset Acquisition
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995507 - Disclosure - Fair Value Measurements
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995517 - Disclosure - Available-for-Sale Securities
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995527 - Disclosure - Prepaid Expenses and Other Current Assets
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995537 - Disclosure - Property and Equipment
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995547 - Disclosure - Accrued Expenses and Other Current Liabilities
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995557 - Disclosure - Equity-Based Compensation
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995567 - Disclosure - Leases
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995577 - Disclosure - Commitments and Contingencies
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995587 - Disclosure - License Agreements
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995597 - Disclosure - Net Loss per Share
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995607 - Disclosure - Income Taxes
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995617 - Disclosure - Defined Contribution Plan
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995627 - Disclosure - Restructuring
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995637 - Disclosure - Segment Reporting
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995647 - Disclosure - Subsequent Events
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995657 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995667 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995677 - Disclosure - Collaborations (Tables)
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995687 - Disclosure - Fair Value Measurements (Tables)
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995697 - Disclosure - Available-for-Sale Securities (Tables)
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995707 - Disclosure - Prepaid Expenses and Other Current Assets (Tables)
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995717 - Disclosure - Property and Equipment (Tables)
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995727 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995737 - Disclosure - Equity-Based Compensation (Tables)
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995747 - Disclosure - Leases (Tables)
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995757 - Disclosure - Net Loss per Share (Tables)
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995767 - Disclosure - Income Taxes (Tables)
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995777 - Disclosure - Restructuring (Tables)
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995787 - Disclosure - Segment Reporting (Tables)
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995797 - Disclosure - Nature of the Business - Additional Information (Detail)
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995807 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995817 - Disclosure - Summary of Significant Accounting Policies - Summary of Property and Equipment Estimated Useful Life (Details)
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995827 - Disclosure - Collaborations - Additional Information (Detail)
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995837 - Disclosure - Collaborations - Summary of Changes in Balances of Company's Related Party Collaboration Receivables and Contract Liabilities (Detail)
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995847 - Disclosure - FA212 Asset Acquisition - Additional Information (Detail)
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995857 - Disclosure - Fair Value Measurements - Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail)
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995867 - Disclosure - Fair Value Measurements - Additional Information (Detail)
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995877 - Disclosure - Fair Value Measurements - Summary of Significant Unobservable Inputs Used in Valuing Developmental Milestone Derivative Liabilities (Detail)
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995887 - Disclosure - Fair Value Measurements - Summary of Fair Value of Derivative Liabilities (Detail)
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995897 - Disclosure - Available-for-Sale Securities - Schedule of Available-for-Sale Securities (Detail)
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995907 - Disclosure - Available-for-Sale Securities - Additional Information (Detail)
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995917 - Disclosure - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Detail)
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995927 - Disclosure - Property and Equipment - Summary of Property and Equipment (Detail)
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995937 - Disclosure - Property and Equipment - Additional Information (Detail)
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995947 - Disclosure - Accrued Expenses and Other Current Liabilities - Summary of Accrued Expenses and Other Current Liabilities (Detail)
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995957 - Disclosure - Equity-Based Compensation - Schedule of Equity-based Compensation Expense (Detail)
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995967 - Disclosure - Equity-Based Compensation - Additional Information (Detail)
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995977 - Disclosure - Equity-Based Compensation - Summary of Stock Option Activity (Detail)
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995987 - Disclosure - Equity-Based Compensation - Summary of Assumptions Used in Black-Scholes Option-Pricing Model for Stock Options Granted (Detail)
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995997 - Disclosure - Equity-Based Compensation - Summary of Restricted Stock Unit Activity (Detail)
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996007 - Disclosure - Equity-Based Compensation - Summary of Performance Stock Units Activity (Details)
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996017 - Disclosure - Leases - Additional Information (Detail)
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996027 - Disclosure - Leases - Future Minimum Payments for Operating and Finance Leases (Detail)
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996037 - Disclosure - Leases - Future Minimum Payments for Operating and Finance Leases (Detail) 2
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996047 - Disclosure - Leases - Summary of Components of Lease Costs (Detail)
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996057 - Disclosure - Leases - Summary of Weighted Average Remaining Lease Term and Discount Rate (Detail)
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996067 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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996077 - Disclosure - License Agreements - Additional Information (Detail)
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996087 - Disclosure - Net Loss per Share - Schedule Computation of Basic and Diluted Net Loss per Share (Detail)
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996097 - Disclosure - Net Loss per Share - Additional Information (Details)
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996107 - Disclosure - Net Loss per Share - Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share (Detail)
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996117 - Disclosure - Income Taxes - Additional Information (Detail)
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996127 - Disclosure - Income Taxes - Summary of Income from Continuing Operations Before Income Tax (Details)
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996137 - Disclosure - Income Taxes - Schedule of Reconciliation of Income Taxes Computed by U.S. Federal Statutory Rate (Detail)
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996147 - Disclosure - Income Taxes - Schedule of Reconciliation of Income Taxes Computed by U.S. Federal Statutory Rate (Detail) 2
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996157 - Disclosure - Income Taxes - Schedule of Net Deferred Tax Assets (Detail)
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996167 - Disclosure - Income Taxes - Schedule of Deferred Income Tax Asset Valuation Allowance (Detail)
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996177 - Disclosure - Defined Contribution Plan - Additional Information (Detail)
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996187 - Disclosure - Restructuring- Additional Information (Detail)
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996197 - Disclosure - Restructuring - Schedule of Balance of Accrued Restructuring Charges and Changes in Accrued Amounts in Connection with Associated Restructuring Plans (Detail)
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996207 - Disclosure - Segment Reporting - Additional Information (Detail)
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996217 - Disclosure - Segment Reporting - Schedule of Segment Expenses, Other Segment Items, and Segment Net Loss (Detail)
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996227 - Disclosure - Subsequent Events - Additional Information (Details)
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Related party transaction, payment
Related Party Transaction Payment
Related party transaction, payment.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Vested
Releases
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from Sale of Property, Plant, and Equipment
Proceeds from sale of property and equipment
Other Research and Development Expense
Research and development expense, other
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Foreign
External Research And Development Expense S G T 003 [Member]
External research and development expense SGT-003.
External R&D expense - SGT-003 [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number, Beginning Balance
Stock units outstanding
Operating lease, monthly payments.
Operating Lease Monthly Payments
Operating lease, monthly payments
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Finance Lease, Liability, to be Paid, Year Four
2029
Preferred Stock, Shares Issued
Preferred stock, shares issued
Statement of Financial Position Location, Balance [Domain]
Balance Sheet Location
Maugeri License Agreement [Member]
Maugeri license agreement member.
Maugeri License Agreement [Member]
Tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Amount [Abstract]
Change in Fair Value Of Derivative Liabilities
Change in fair value of derivative liabilities.
Change in fair value of derivative liabilities
Change in fair value of derivative liabilities
Change in fair value of derivative liabilities
Change in fair value of derivative liabilities
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing, financing, and operating activities:
Plan Name [Axis]
Plan Name
Prepaid other and other current assets
Prepaid Other and Other Current Assets
Prepaid other and other current assets.
Entity Current Reporting Status
Entity Current Reporting Status
Amendment and Restatement of ESPP [Member]
Amendment and Restatement of ESPP [Member]
Amendment and restatement of ESPP member.
Operating Expenses [Abstract]
Operating expenses:
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted Average Exercise Price
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
MASSACHUSETTS
Cambridge, Massachusetts [Member]
Product and Service [Axis]
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In To Level 1.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In To Level 1
Fair value, assets, transfers into level 1, amount
Amended and restated two thousand and twenty incentive plan.
Amended and Restated Two Thousand And Twenty Incentive Plan [Member]
Amended and Restated 2020 Plan [Member]
Document Fiscal Period Focus
Document Fiscal Period Focus
Finance Lease, Liability, to be Paid
Future minimum lease commitment
Total future minimum lease payments
Hood Park LLC.
Hood Park L L C [Member]
Hood Park LLC [Member]
Entity Shell Company
Entity Shell Company
Segment Reporting, Policy [Policy Text Block]
Segment Data
Annual Know How Access Fee
Annual know how access fee.
Annual know-how access fee
Cash and cash equivalents as presented on balance sheet
Cash and Cash Equivalent
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Restructuring charges expected to be paid.
Restructuring charges expected to be paid
Restructuring charges expected to be paid
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common Stock, Shares, Issued
Common stock, shares issued
Cybersecurity Risk Board of Directors Oversight [Text Block]
Lessee, Operating Lease, Description
Lease description
Milestone payment.
Milestone Payment
Milestone payment
Statement [Table]
Statement [Table]
Prepaid expenses and other current assets.
Prepaid Expenses And Other Current Assets [Text Block]
Prepaid Expenses and Other Current Assets
Restricted cash noncurrent
Restricted cash, non-current, as presented on balance sheet
Restricted cash, non-current
Restricted cash, net of current portion
FA212 LLC [Member]
FA212 LLC [Member]
FA212 LLC.
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Operating lease liabilities arising from obtaining right-of-use-assets
Right-of-use assets obtained in exchange for operating lease liabilities
Sale [Member]
Sale.
Sale [Member]
Ultragenyx [Member]
Ultragenyx [Member]
Ultragenyx
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value of stock options granted
Asset Acquisition Transaction Costs
Asset acquisition transaction costs.
Transaction costs
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Revenue from Contract with Customer [Policy Text Block]
Revenue
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Expired
Warrant [Member]
Warrants [Member]
Entity Filer Category
Entity Filer Category
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Units
Liabilities and Equity
Total liabilities and stockholders' equity
Payables and Accruals [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable at December 31, 2025
Restructuring Type [Axis]
Restructuring Type
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Severance Costs
Restructuring charges related to severance payment and other employee-related costs
Restructuring charges related to severance payment and other employee-related costs
Finance Lease, Liability, to be Paid, Year Three
2028
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Summary of Fair Value of Derivative Liabilities
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increases recorded to income tax provision
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Valuation allowance at beginning of year
Valuation allowance at end of year
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Income tax computed at U.S. federal statutory tax rate
Shares Issued, Price Per Share
Common stock issued price per share
Subsequent Event [Line Items]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount, Total
Nontaxable or nondeductible items
Adjustments to Additional Paid in Capital, Pre-funded Warrants Issued, Issuance Costs
Adjustments to additional paid in capital, pre-funded warrants issued, issuance costs.
Pre-funded warrants issuance costs
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Other Noncash Income (Expense)
Other Noncash Income (Expense), Total
Other
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Expected Dividend
Expected dividend yield
Effective Income Tax Rate Reconciliation, Percent
Total
Options to Purchase Common Stock [Member]
Investment Income, Interest
Interest income, net
Interest income
Interest income
Income Tax Jurisdiction [Axis]
Income Tax Authority
University of Washington license agreement
University Of Washington License Agreement [Member]
University of Washington [Member]
Derivative Liability, Measurement Input
Derivative Liabilities, Unobservable Input
Geographical [Domain]
Geographical
Mayo [Member]
Mayo.
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of underwriting discounts and commissions
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of underwriting discounts and commissions.
Proceeds from issuance of common stock and pre-funded warrants in public offering, net of underwriting discounts and commissions
Non-current assets:
Assets, Noncurrent [Abstract]
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block]
Schedule of Reconciliation of Segment Net Loss to Consolidated Net Loss
Schedule of Segment Expenses, Other Segment Items, and Segment Net Loss
Decrease in right-of-use asset and lease liability due to lease termination
Increase decrease in right of use asset and lease liability due to lease termination.
Increase Decrease In Right Of Use Asset And Lease Liability Due To Lease Termination
Additional Paid in Capital, Common Stock
Additional paid-in capital
Related Party [Member]
Related Party [Member]
Office laboratory.
Office Laboratory [Member]
Office laboratory [Member]
Defined Contribution Plan [Text Block]
Defined Contribution Plan
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Accrued expenses and other current liabilities.
Accrued Expenses And Other Current Liabilities Table [Text Block]
Summary of Accrued Expenses and Other Current Liabilities
Vesting [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted
Granted
Finance liabilities and finance lease sale and lease back liabilities current and noncurrent.
Finance Liabilities And Finance Lease Sale And Lease Back Liabilities Current And Noncurrent
Total Lease Liabilities
Cybersecurity Risk Management, Strategy, and Governance [Table]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Computation of Basic and Diluted Net Loss per Share
Investments Classified by Contractual Maturity Date [Table Text Block]
Summary Estimated Fair Value and Amortized Cost of Available-for-Sale Securities by Contractual Maturity
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Stock options outstanding
Outstanding at January 1, 2025
Outstanding at December 31, 2025
Stock Issued
Issuance of common stock in acquisition
Liabilities, Current
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Summary of Significant Unobservable Inputs Used in Valuing Developmental Milestone Derivative Liabilities
Domestic Tax Jurisdiction [Member]
Domestic Tax Authority [Member]
Effective Income Tax Rate Reconciliation, Tax Credit, Percent [Abstract]
Tax credits
Schedule of Property and Equipment Estimated Useful Life [Table Text Block]
Schedule of property and equipment estimated useful life.
Schedule of Property and Equipment Estimated Useful Life
Accounting Standards Update [Axis]
Accounting Standards Update
Consolidation Items [Domain]
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Number of headcount reduced, percentage
Number of headcount reduced, percentage
Equity, Attributable to Parent [Abstract]
Stockholders equity:
Entity Small Business
Entity Small Business
Available For Sale Securities Weighted Average Maturity period
Available For Sale Securities Weighted Average Maturity Period
Available-for-sale securities weighted average contractual maturity period
Weighted-average remaining lease term.
Weighted Average Remaining Lease Term [Abstract]
Weighted-average remaining lease term (in years)
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock compensation
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Forfeitures
Proceeds from Issuance Initial Public Offering
Net proceeds from offering
Share-Based Payment Arrangement [Text Block]
Equity-Based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Lease Contractual Term [Axis]
Lease Contractual Term
Leases [Abstract]
Adjustments to Additional Paid in Capital, Net Of Sales Commissions
Adjustments to additional paid in capital, net of sales commissions.
Sales commissions
Deferred revenue - related party
Contract with Customer, Liability
Deferred revenue, Ending balance
Deferred revenue, Beginning balance
Contract with Customer, Liability, Total
Deferred revenue
Amendment
Amendment Flag
Amendment Flag
Product and Service [Domain]
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Income tax computed at U.S. federal statutory tax rate
Earnings Per Share, Policy [Policy Text Block]
Net Loss per Share
Proceeds from Repayment of Loans by Employee Stock Ownership Plans
Employee stock purchase plan purchases
Liabilities and Stockholders' Equity
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Change in operating lease liability
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Commitment And Contingencies [Table]
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Segment reporting, CODM, profit (loss) measure, how used, description
Common Stock [Member]
Common Stock [Member]
Common Stock [Member]
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In to Level 2
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers In to Level 2
Fair value, assets, transfers into level 2, amount
Cybersecurity Risk Role of Management [Text Block]
Tax Credit Carryforward, Amount
Tax credits carryforwards
Defined Contribution Plan, Employer Discretionary Contribution Amount
Company's contribution to the plan
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Less accumulated depreciation and amortization
Debt Securities, Available-for-Sale [Line Items]
Debt Securities, Available-for-sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Operating Loss Carryforwards Expiration Period
Operating loss carryforwards, expiration period.
Operating loss carryforwards, expiration period
Entity Address, Address Line One
Entity Address, Address Line One
Entity Address, Address Line One
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers out of Level 3
Fair value, assets, transfers out of level 3, amount
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Assumptions Used in Black-Scholes Option-Pricing Model for Stock Options Granted
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Construction allowance.
Construction Allowance
Construction allowance
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income Taxes
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flow information:
Name of Property
Name of Property [Axis]
Statement of Financial Position Location, Balance [Axis]
Balance Sheet Location
Operating Lease, Right-of-Use Asset
Written off amount of the right-of-use asset
Operating lease, right-of-use assets
Deferred Tax Assets, Gross
Total deferred tax assets
Derivative liability
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Payments to Acquire Debt Securities, Available-for-Sale
Purchases of available-for-sale securities
Class of Warrant or Right [Axis]
Document Type
Document Type
Document Type
Amended And Restated Two Thousand And Twenty One Employee Stock Purchase Plan [Member]
Amended and restated two thousand and twenty one employee stock purchase plan.
Amended and Restated 2021 Employee Stock Purchase Plan [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Debt Securities, Available-for-Sale [Table Text Block]
Schedule of Available-for-Sale Securities
External General And Administrative Expense Facilities [Member]
External general and administrative expense facilities.
External G&A Expense - Facilities [Member]
Asset Acquisition [Table]
Investments, Debt and Equity Securities [Abstract]
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net (decrease) increase in cash, cash equivalents and restricted cash
Mayo Clinic Collaboration And License Agreement [Member]
Mayo clinic collaboration and license agreement.
Mayo Clinic Collaboration and License Agreement [Member]
Subsequent Event Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Common stock equivalents excluded from calculation of diluted net loss per share
Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share
Deferred Compensation Arrangement with Individual, Common Stock Reserved for Future Issuance
Number of share reserved for future issuance
Asset Acquisition, Assumed Cumulative Sales Milestone Payments
Asset acquisition, assumed cumulative sales milestone payments.
Assumed cumulative sales milestone payments
Reconciliation of Segment Profit or Loss [Member]
Eliminations And Reconciling Items [Member]
Eliminations and reconciling Items.
Common Stock, Par or Stated Value Per Share
Common stock, par value
Accounting Standards Update [Domain]
Accounting Standards Update
Accrued restructuring charges, ending balance
Accrued restructuring charges, beginning balance
Accrued restructuring costs
Accrued restructuring costs.
Share-Based Payment Arrangement, Tranche One [Member]
Tranche One [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding
Stock options outstanding, weighted average recognition period
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, Maximum
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Components of Deferred Tax Assets and Liabilities [Abstract]
Debt Securities, Available-for-Sale
Total available-for-sale securities, fair value
Fair Value
Total available-for-sale securities
Income from continuing operations before income tax
Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest [Abstract]
Document Financial Statement Error Correction [Flag]
Operating lease payments annual escalation percentage.
Operating Lease Payments Annual Escalation Percentage
Operating lease payments annual escalation percentage
Reconciliation Of Beginning And End Of Period Amounts From Cash Flow Statement To Balance Sheet Table [Text Block]
Reconciliation Of Beginning And End Of Period Amounts From Cash Flow Statement To Balance Sheet Table [Text Block]
Reconciliation of Amounts From Cash Flow Statement to Balance Sheet
Outlicense Agreements [Member]
Outlicense Agreements.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of common stock options, shares
Exercised
Stock options exercised
Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block]
Fair Value Measurements
Accrued Liabilities, Current
Accrued expenses
Accrued expenses and other current liabilities
Accrued Liabilities, Current, Total
Accrued compensation.
Accrued Compensation [Member]
Accrued Compensation [Member]
Assumed contingent development milestone payments
Asset Acquisition, Assumed Contingent Development Milestone Payments
Asset acquisition, assumed contingent development milestone payments.
Stock Issued During Period, Value, Restricted Stock Award, Gross
Vesting of restricted stock units
External Research And Development Other [Member]
External research and development other.
External Research and Development Other [Member]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Address, State or Province
Entity Address, State or Province
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Nonvested RSUs/PSUs at December 31, 2025
Nonvested RSUs/PSUs at January 1, 2025
MOROCCO
MOROCCO
Asset Acquisition [Domain]
Financial Liabilities Fair Value Disclosure
Total financial liabilities
Total financial liabilities
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Gross Unrealized Gain
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Class of Warrant or Right [Domain]
Lessee lease liability maturity.
Lessee Lease Liability Maturity Table [Text Block]
Future Minimum Payments for Operating and Finance Leases
Geographical [Axis]
Geographical
Other Agreements [Member]
Other agreements.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Equity-based Compensation Expense
Finance Lease, Liability, to be Paid, after Year Five
Thereafter
Stock Issued During Period, Value, Stock Options Exercised
Exercise of common stock options
Intrinsic value of stock options exercised
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Expenses and Other Current Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Net Deferred Tax Assets
Collaborative Arrangement Disclosure [Text Block]
License Agreements
Performance Shares [Member]
Nonvested Performance Stock Units [Member]
Performance Stock Units [Member]
Non cash Lease Expense
Non-cash lease expense.
Non-cash lease expense
Subsequent Event [Member]
Subsequent Event [Member]
Marketable Securities, Policy [Policy Text Block]
Available-for-Sale Securities
Issuance Of Common Stock In Private Placement For Payment Of Developmental Milestone Consideration
Issuance of common stock in private placement for payment of developmental milestone consideration.
Issuance of common stock in private placement for payment of developmental milestone consideration, units
Property, Plant and Equipment [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Number of additional shares authorized for common stock for equity awards
Number of shares of common stock reserved for issuance
Other Assets, Noncurrent
Other non-current assets
Fair Value Measurement Inputs and Valuation Techniques [Table]
Debt Securities, Available-for-Sale, Current
Available-for-sale securities
Accounts receivable related parties deductions.
Accounts Receivable Related Parties Deductions
Related party collaboration receivable, Deductions
Antidilutive Securities [Axis]
Antidilutive Securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Expired
Expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Percentage of vesting
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Aggregate grant date fair value of RSUs vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Vested and expected to vest, Aggregate Intrinsic Value
State and Local Jurisdiction [Member]
State and Local Jurisdiction [Member]
Milestone payments upon achievement of regulatory milestone.
Milestone Payments Upon Achievement Of Regulatory Milestone
Milestone payments upon achievement of regulatory milestone
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Other Comprehensive Income [Member]
Derivative Liability, Total
Derivative liabilities at fair value
Derivative liabilities at fair value
Fair value of derivative liabilities as of December 31, 2025
Fair value of derivative liabilities as of January 1, 2025
Derivative liabilities
Cash and Cash Equivalents [Domain]
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value; 10,000,000 shares authorized at December 31, 2025 and 2024; no shares issued and outstanding at December 31, 2025 and 2024
Deferred tax liabilities depreciation.
Deferred Tax Liabilities Depreciation
Depreciation
Finance Lease Interest Expense (Reversal)
Finance lease interest expense (reversal).
Interest of finance leases
Minimum [Member]
Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Granted
Weighted average grant date fair value
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Finance Leases Liability Undiscounted Excess Amount
Finance leases liability undiscounted excess amount.
Less: Imputed Interest
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table]
Fair Value, Inputs, Level 3 [Member]
Level 3 [Member]
Liabilities, Fair Value Disclosure [Abstract]
Financial liabilities
Financial liabilities
One-time upfront payment in shares
One Time Upfront Payment In Shares
One time upfront payment in shares.
AavantiBio, Inc.
AavantiBio, Inc [Member]
Segment Reporting [Abstract]
Business Combination [Policy Text Block]
Business Combinations
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis
Liabilities, Current [Abstract]
Current liabilities:
Restructuring and Related Activities Disclosure [Text Block]
Restructuring
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 1.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 1
Fair value, assets, transfers out of level 1, amount
Segment Reporting, Other Segment Item, Composition, Description
January 2020 Plan.
January 2020 Plan [Member]
Effective Income Tax Rate Reconciliation Federal Orphan Drug Credit
Effective income tax rate reconciliation federal orphan drug credit.
Federal orphan drug credit
Shares, Outstanding
Ending balance, units
Beginning balance, units
Sublease Income
Sub-lease income
Sub-lease income
Operating Loss Carryforwards
Net operating loss carryforwards
Related party collaboration receivables
Related party collaboration receivables, Ending balance
Related party collaboration receivables, Beginning balance
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Lessee, Operating Lease, Renewal Term
Lease renewal term
Gabriel Brooks, M.D [Member]
Gabriel Brooks, M.D.
Gabriel Brooks, M.D [Member]
University of Missouri License Agreement
University Of Missouri License Agreement [Member]
University of Missouri [Member]
Commitments and Contingencies
Commitments and contingencies (Note 11)
Lessee, Leases [Policy Text Block]
Leases
Income Taxes [Table]
Income Taxes [Table]
Income Taxes [Table]
Cumulative Developmental Milestones
Cumulative developmental milestones .
Cumulative developmental milestones
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Nonvested RSUs/PSUs at December 31, 2025
Nonvested RSUs/PSUs at January 1, 2025
Accrued Milestone Payment [Member]
Accrued milestone payment.
Accrued Milestone Payment [Member]
General and Administrative Expense [Member]
General and Administrative Expenses [Member]
Operating Lease, Liability
Lease liability
Operating Lease, Liability, Total
Written off amount of the remaining lease liability
Auditor Firm ID
Auditor Firm ID
Forecast [Member]
Forecast
Restricted Cash, Current
Restricted cash, current
Common Stock Issued As Payment For Developmental Milestone Consideration
Common stock issued as payment for developmental milestone consideration.
Common stock issued as payment for developmental milestone consideration
Gain (Loss) on Derivative Instruments, Net, Pretax
Gain (Loss) on Derivative Instruments, Net, Pretax, Total
Change in fair value of derivative liabilities
Asset Acquisitions [Policy Text Block]
Asset acquisitions.
Asset Acquisitions
Finance lease liabilities
Finance Lease, Liability, Current
Prepaid research and development expenses, current.
Prepaid Research And Development Expenses Current
Prepaid research and development expenses
Finance Lease, Weighted Average Discount Rate, Percent
Finance leases
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Liabilities, Noncurrent [Abstract]
Non-current liabilities:
Schedule of Restructuring Reserve by Type of Cost [Table Text Block]
Schedule of Balance of Accrued Restructuring Charges and Changes in Accrued Amounts in Connection with Associated Restructuring Plans
Capital Expenditures Incurred but Not yet Paid
Property and equipment purchases included in accounts payable and accruals
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net loss
Net losses
Consolidated net loss
Lease Contractual Term [Domain]
Lease Contractual Term
Share-Based Payment Arrangement, Recognized Amount [Abstract]
Development Milestone Payments
Development milestone payments.
Development milestone payments
Deferred tax liabilities right of use asset.
Deferred Tax Liabilities Right Of Use Asset
Right-of-use asset
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted average shares of common stock outstanding used to compute basic net loss per share
Weighted average shares of common stock outstanding, basic
Weighted average shares of common stock outstanding used to compute basic net loss per share
First development milestone payment in shares
First development milestone payment in shares.
Scenario [Axis]
Scenario
Payments for (Proceeds from) Available-for-Sale Securities, Short-Term
Proceeds from sales and maturities of available-for-sale securities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Intrinsic value of stock options exercisable
Exercisable, Aggregate Intrinsic Value
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Reconciliation of Income Taxes Computed by U.S. Federal Statutory Rate
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Arkea Bio Corp [Member]
Arkea Bio Corp [Member]
Arkea bio corp.
Financing cash flows for finance leases, cash paid for interest
Financing cash flows for finance leases cash paid for interest.
Financing cash flows for finance leases
Proceeds from Issuance of Private Placement
Net proceeds from private placement
Company received net proceeds
Decrease in property, plant and equipment due to asset exchange
Increase Decrease in property plant and equipment due to asset exchange
Increase Decrease in property plant and equipment due to asset exchange
Subsequent Events
Subsequent Events [Text Block]
Asset Acquisition, Consideration Transferred, Transaction Cost
Aggregate acquisition cost
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Equity-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Deferred Tax Asset, In-Process Research and Development
Capitalized R&D
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance
Timing of Achieving Certain Development Milestones [Member]
Timing Of Achieving Certain Development Milestones [Member]
Timing of achieving certain development milestones.
Equity, Attributable to Parent
Total stockholders' equity
Ending balance
Beginning balance
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Statement of Stockholders' Equity [Abstract]
Funding from charitable organizations.
Funding From Charitable Organizations [Member]
Funding From Charitable Organizations [Member]
Tranche Two [Member]
Share-Based Payment Arrangement, Tranche Two [Member]
Type of Restructuring [Domain]
Type of Restructuring
Use of Estimates, Policy [Policy Text Block]
Significant Judgments and Estimates
building interior [Member]
Building interior.
Building Interior [Member]
Accrued Expenses And Other Current Liabilities [Line Items]
Accrued Expenses And Other Current Liabilities [Line Items]
Accrued Expenses And Other Current Liabilities [Line Items]
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Two Thousand and Twenty Four Inducement Stock Incentive Plan [Member]
Two thousand and twenty four inducement stock incentive plan.
2024 Inducement Stock Incentive Plan [Member]
Collaborations.
Collaborations [Text Block]
Collaborations
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of Options
Discount Rate [Member]
Measurement Input, Discount Rate [Member]
Contract with customer liability deductions.
Contract With Customer Liability Deductions
Deferred revenue, Deductions
Upfront payment
Asset Acquisition Upfront Payment
Asset Acquisition Upfront Payment
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, Other Segment Item, Amount
Other segment items
Plan Name
Plan Name [Domain]
Software and Software Development Costs [Member]
Computer Software [Member]
Agreement termination notice period
Cumulative sales milestone payments
Cumulative Sales Milestone Payments
Cumulative sales milestone payments.
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Impairment loss
Impairment, Long-Lived Asset, Held-for-Use
Impairment, Long-Lived Asset, Held-for-Use, Total
Business Description and Basis of Presentation [Text Block]
Nature of the Business
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Finance Lease, Liability, to be Paid, Year One
2026
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights
Description of vesting rights
Certificates of Deposit [Member]
Certificates of Deposit [Member]
Pre-funded warrants to purchase shares of common stock
Class of Warrant or Right, Outstanding
Significant Accounting Policies [Line Items]
Significant Accounting Policies [Line Items]
Significant Accounting Policies [Line Items]
Issuance of common stock in private placement for payment of developmental milestone consideration
Issuance Of Common Stock Value In Private Placement For Payment Of Developmental Milestone Consideration
Issuance of common stock value in private placement for payment of developmental milestone consideration.
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Operating Leases
Restructuring Plan [Axis]
Related and Nonrelated Parties [Axis]
FA212 Asset Acquisition
Asset Acquisition [Text Block]
Other items
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Percentage Of Annual Taxable Income
Percentage of annual taxable income.
Percentage of annual deduction equal to annual taxable income
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Operating loss carryforwards amount on expiration.
Operating Loss Carryforwards Amount on Expiration
Operating loss carryforwards, expiration
Area of Real Estate Property
Area of lease agreement
Area of subleased agreement
Entity Address, City or Town
Entity Address, City or Town
Number of reportable segment
Number of Reportable Segments
Security Exchange Name
Security Exchange Name
Other items
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Property, Plant and Equipment, Gross
Property and equipment, gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Counterparty Name [Axis]
Counterparty Name
Total worldwide income from continuing operations before income tax
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest as of December 31, 2025
Shares issued for first milestone payment
Shares Issued for Milestone Payment
Shares issued for milestone payment.
Internal General And Administrative Expense [Member]
Internal general and administrative expense.
Internal General and Administrative Expense [Member]
Maximum Milestone Payment Upon Achievement Of Specified Commercial Milestone Events
Maximum milestone payment upon achievement of specified commercial milestone events.
Maximum milestone payment upon achievement of specified commercial milestone events
Measurement Input Type [Domain]
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, cash equivalents, and restricted cash at end of period
Cash, cash equivalents, and restricted cash at beginning of period
Total cash and cash equivalents, and restricted cash, as reported in the condensed consolidated statements of cash flows
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Statistical Measurement [Domain]
Statistical Measurement
Alexander Cumbo [Member]
Alexander Cumbo.
Alexander Cumbo [Member]
Common stock warrants price per share
Class of Warrant or Right, Exercise Price of Warrants or Rights
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Period End Date
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Amount payable in connection with execution of collaboration agreement
Milestone amount payable in connection with agreement.
Milestone Amount Payable In Connection With Agreement
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Exercisable at December 31, 2025
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
'Restricted Stock Units (RSUs) [Member]
Nonvested Restricted Stock Units [Member]
Accrued Other and Other Current Liabilities [Member]
Accrued Expenses Other and Other Current Liabilities [Member]
Accrued espenses other and other current liabilities.
February 2025 Offering [Member]
February 2025 offering.
February 2025 Offering [Member]
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Vesting [Axis]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Other comprehensive income:
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Related party collaboration receivables, Additions
Contract With Customer Liabilities Current Additions
Contract with customer liabilities current additions.
Deferred Tax Liabilities, Net
Total deferred tax liabilities
Deferred Tax Liabilities, Net, Total
Related party collaboration receivables
Other Receivables
Related party collaboration receivables
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Finance Leases
Liabilities
Total liabilities
Issuance of common stock value in private placement for upfront consideration
Issuance of common stock value in private placement for upfront consideration.
Issuance of common stock in private placement for upfront consideration, shares
Financial Instruments [Domain]
Probability Of Achieving Certain Development Milestones [Member]
Probability of achieving certain development milestones.
Probability of Achieving Certain Development Milestones [Member]
License agreement termination expiration term.
License Agreement Termination Expiration Term
License agreement termination expiration term
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Restricted Cash
Restricted cash
Restricted Cash, Total
Class of warrant or rights exercised.
Class Of Warrant Or Rights Exercised
Warrants exercised
Indefinite-Lived Intangible Assets, Major Class Name [Domain]
Indefinite-lived Intangible Assets, Major Class Name
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average shares of common stock outstanding, used to compute diluted net loss per share
Weighted average shares of common stock outstanding, diluted
Research contract costs and accruals.
Research Contract Costs And Accruals Policy [Text Block]
Research Contract Costs and Accruals
Entity File Number
Entity File Number
Percentage of option to fund of development cost.
Percentage Of Option To Fund Of Development Cost
Percentage of option to fund of development cost
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized gain on available-for-sale securities
Unrealized gain on available-for-sale securities
Cover
Cover [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, Minimum
Measurement Input Type [Axis]
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Prepaid expenses and other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Forfeitures
Forfeitures
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Percentage of number of shares outstanding
Summary of Valuation Allowance [Table Text Block]
Schedule of Deferred Income Tax Asset Valuation Allowance
Subleased description
Subleased description.
Scenario [Domain]
Scenario
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Number of shares authorized for common stock for equity awards
Number of Operating Segments
Number of operating segment
Sale of Stock [Domain]
Sale of Stock
Segment Reporting Disclosure [Text Block]
Segment Reporting
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
General and administrative expense
External Research And Development Expense S G T 001 [Member]
External research and development expense SGT-001.
External R&D Expense - SGT-001 [Member]
Non Cash Acquired In Process Research And Development
Non cash acquired in process research and development.
Non-cash acquired in-process research and development
Share-Based Payment Arrangement, Performance Shares, Activity [Table Text Block]
Summary of Performance Stock Units Activity
Offering period
Share Based Compensation Arrangement By Share Based Payment Award Offering Period
Share based compensation arrangement by share based payment award offering period.
Subsequent Event [Table]
Deferred Tax Assets, Other
Other
Paul Herzich [Member]
Paul Herzich.
Paul Herzich [Member]
Deferred tax assets tax deferred accrued expense.
Deferred Tax Assets Tax Deferred Accrued Expense
Accrued expenses
Adjustments to Additional Paid in Capital, Warrant Issued
Issuance of pre-funded warrants in public offering/private placement
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions Common Stock Price
Share-based compensation arrangement by share-based payment award, fair value assumptions common stock price.
Common stock price
External General and Administrative Expense [Member]
External General And Administrative Expense [Member]
External general and administrative expense.
Contract With Customer Liabilities Current Deductions
Contract with customer liabilities current deductions.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Vested and expected to vest as of December 31, 2025
Accrued Research and Development Expense [Member]
Accrued Research And Development Expense [Member]
Accrued research and development expense.
Accrual recorded as a result of restructuring charges
Restructuring Charges
Restructuring expense
Restructuring Charges, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Remaining Contractual Life (in years)
Property, Plant and Equipment, Useful Life
Useful life of asset
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Pronouncements
Issued and sold shares of common stock
Issuance of common stock in connection with employee stock purchase plan, units
Issuance of common stock to related party in connection with stock purchase agreement.
Issuance Of Common Stock To Related Party In Connection With Stock Purchase Agreement
Financing Cash Flows For Finance Leases Principal Portion of Finance Lease Payment
Financing cash flows for finance leases principal portion of finance lease payment.
Financing cash flows for finance leases
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of Unvested Restricted Shares of Common Stock Activity
Deferred revenue, Ending balance
Deferred revenue, Beginning balance
Contract with Customer, Liability, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Financial Liabilities Fair Value Disclosure [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free rate, Minimum
Income (Loss) from Continuing Operations before Income Taxes, Domestic
United States
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized equity-based compensation
Collaboration agreement related costs
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross
Lessee, Operating Lease, Term of Contract
Lease term
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Operating Lease, Liability, Current
Operating lease liabilities, current
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
At The Market Public Offering [Member]
At the market public offering.
At-the-Market Public Offering [Member]
Document Transition Report
Document Transition Report
Share-Based Payment Arrangement, Additional Disclosure [Abstract]
Deferred Tax Assets, Net
Net deferred taxes
Operating Expenses
Total operating expenses
Research and Development Expense
Research and development
Research and development expense
Research and Development Expense, Total
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest
Comprehensive loss
Statement of Cash Flows [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-Average Grant Date Fair Value
Stock Issued During Period, Value, New Issues
Issuance of common stock, net of issuance costs
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
Assets, Fair Value Disclosure [Abstract]
Financial assets
Summary of Weighted Average Remaining Lease Term and Discount Rate
Weighted Average Remaining Lease Term And Discount Rate [Table Text Block]
Weighted average remaining lease term and discount rate.
Proceeds from Issuance of Common Stock in Public Offering, Net of Sales Commissions
Proceeds from issuance of common stock in public offering, net of sales commissions.
Proceeds from issuance of common stock in at-the-market public offering, net of sales commissions
Earnings Per Share [Text Block]
Net Loss per Share
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of Restricted Stock Unit Activity
Computer Equipment [Member]
Computer Equipment [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Stock options outstanding, intrinsic value
Outstanding, Aggregate Intrinsic Value
2020 equity incentive plan.
Two Thousand And Twenty Equity Incentive Plan [Member]
2020 Equity Incentive Plan [Member]
Transaction price.
Transaction Price
Transaction price
Operating Lease, Cost
Operating lease costs
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividends
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Earnings Per Share Basic [Line Items]
Liability for Uncertainty in Income Taxes, Current
Uncertain tax position
First development milestone payable
First development milestone payable.
S G T 003 [Member]
SGT-003.
SGT-003 [Member]
Office and laboratory lease.
Office And Laboratory Lease [Member]
Office and Laboratory Lease [Member]
Operating Lease, Payments
Operating cash flows for operating leases
Assets
Assets [Abstract]
Construction in Progress [Member]
Construction in Progress [Member]
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current and non-current assets
Name of Property [Domain]
Name of Property
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
Changes in unrecognized tax benefits
Effective Income Tax Rate Reconciliation Unrecognized Tax Benefits
Effective income tax rate reconciliation unrecognized tax benefits.
Deferred Tax Assets, Tax Deferred Expense, Total
Deferred Tax Assets, Tax Deferred Expense
Deferred expenses
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities:
Retirement Benefits [Abstract]
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense
Interest expense
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Schedule of Income from Continuing Operations Before Income Tax
Research and Development Expense [Member]
Research and Development Expenses [Member]
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Available-for-Sale Securities
Upfront license fee
Upfront License Fee
Upfront license fee.
Summary of Changes in Balances of Company's Related Party Collaboration Receivables and Contract Liabilities
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Schedule of Prepaid Expenses and Other Current Assets
Asset Acquisition, Date of Acquisition Agreement
Agreement date
Restructuring Cost and Reserve [Line Items]
Components of Deferred Tax Assets [Abstract]
Deferred tax assets:
Repayment of Long-Term Debt, Long-Term Lease Obligation, and Capital Security
Repayment of Long-Term Debt, Long-Term Lease Obligation, and Capital Security, Total
Payments of principal portion of finance lease obligations
November 2022 Plan.
November 2022 Plan Member
November 2022 Plan [Member]
License agreement termination expiration term for licensed product.
License Agreement Termination Expiration Term for Licensed Product
License agreement termination expiration term for licensed product
Proceeds from Stock Options Exercised
Proceeds from exercises of common stock options
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Lab space.
Lab Space [Member]
Lab Space [Member]
Impairment, Long-Lived Asset, Held-for-Use, Statement of Income or Comprehensive Income [Extensible Enumeration]
Payments of common stock and pre funded warrants issuance costs in public offering.
Payments of common stock and pre-funded warrants issuance costs in public offering
Payments of common stock and pre-funded warrants issuance costs in public offering
Share-Based Payment Arrangement [Abstract]
Assets, Fair Value Disclosure
Total financial assets
Unlimited carryforward.
Unlimited Carryforward
Unlimited carryforward amount
Sale of Stock [Axis]
Sale of Stock
Collaboration revenue - related party
Revenues
Revenues, Total
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash used in investing activities
Transaction price determined under ASC 606
Transaction Price Determined Under A S C 606
Transaction price determined under ASC 606.
January 2024 Private Placement [Member]
Private Placement [Member]
Private Placement [Member]
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Fair value, assets, transfers into level 3, amount
Finance Lease, Weighted Average Remaining Lease Term
Finance leases
Title of 12(b) Security
Title of 12(b) Security
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeitures
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Forfeitures
Recognized built in losses.
Recognized Built In Losses [Member]
Money Market Funds [Member]
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Income Tax Disclosure [Text Block]
Income Taxes
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Restructuring Plan [Domain]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Property, Plant and Equipment [Table Text Block]
Summary of Property and Equipment
Letters of Credit Outstanding, Amount
Letter of credit amount
Letter of credit outstanding amount
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Outstanding at January 1, 2025
Outstanding at December 31, 2025
Income Tax Disclosure [Abstract]
April 2022 Plan.
April 2022 Plan Member
April 2022 Plan [Member]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Accrued Liabilities and Other Liabilities [Abstract]
Unrecognized Tax Benefits
Unrecognized tax benefits
Unrecognized Tax Benefits, Beginning Balance
Unrecognized Tax Benefits, Ending Balance
Additional Paid in Capital [Member]
Additional Paid-in Capital [Member]
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Accrued expenses and other current and non-current liabilities
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment
Change in fair value of derivative liabilities
Liabilities, Fair Value Adjustment
Gain (losses) recorded for a change in fair value
Common Stock Issuable Upon Exercise of Prefunded Warrants
Common stock issuable upon exercise of prefunded warrants
Common stock issuable upon exercise of pre-funded warrants
Recently issued accounting pronouncements.
Recently Issued Accounting Pronouncements [Policy Text Block]
Recently Issued Accounting Pronouncements
Recently issued accounting pronouncements
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free rate, Maximum
Nontaxable or nondeductible items
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent, Total
Subsequent Event Type [Axis]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Entity Ex Transition Period
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Future minimum rent commitment
Total future minimum lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: Imputed Interest
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Federal R&D credit
Equity Components [Axis]
Equity Components
Deferred Tax Assets, Derivative Instruments
Derivative liabilities
Significant Accounting Policies [Table]
Significant Accounting Policies [Table]
Significant Accounting Policies [Table]
Unvested Stock Options [Member]
Unvested stock options member.
Unvested Stock Options [Member]
Nonoperating Income (Expense)
Total other income, net
Other income (expense), net
Equity Component [Domain]
Equity Component
Jessie Hanrahan Ph. D. [Member]
Jessie Hanrahan Ph. D.
Jessie Hanrahan Ph. D. [Member]
Document Annual Report
Document Annual Report
Business Combination [Axis]
Class Of Warrant Or Right Price Per Share
Class of warrant or right price per share.
Common stock warrants price per share
Reclassification Of Accrued Milestone Payment To Accrued Expenses And Other Current Liabilities
Reclassification of accrued milestone payment to accrued expenses and other current liabilities.
Reclassification of accrued milestone payment to accrued expenses and other current liabilities
Government Bonds [Member]
Government Bonds.
Government Bonds [Member]
Government Bonds Maturing in One Year or Less [Member]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock under employee stock purchase plan, units
Depreciation, Depletion and Amortization, Nonproduction
Depreciation and amortization expense
Depreciation, Depletion and Amortization, Nonproduction, Total
Statement of Comprehensive Income [Abstract]
Accrued Expenses And Other Current Liabilities [Table]
Accrued Expenses And Other Current Liabilities [Table]
Accrued Expenses And Other Current Liabilities [Table]
Maximum [Member]
Maximum [Member]
Statistical Measurement [Axis]
Statistical Measurement
License agreements termination description.
License Agreements Termination Description
License agreements termination description
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised
One-time Termination Benefits [Member]
One-Time Employee Termination Benefits [Member]
April 2022 Corporate Strategy Change [Member]
April 2022 Corporate Strategy Change.
April 2022 Corporate Strategy Change [Member]
Common Stock, Value, Issued
Common stock, $0.001 par value; 240,000,000 and 120,000,000 shares authorized at December 31, 2025 and 2024, respectively; 78,967,888 and 40,468,141 shares issued and outstanding at December 31, 2025 and 2024, respectively
Common stock issued as up front payment for collaboration and license agreement
Common stock issued as up front payment for collaboration and license agreement.
Common stock issued as upfront payment for collaboration and license agreement
Equipment [Member]
Laboratory Equipment [Member]
Lab Equipment [Member]
Contract with customer liability additions.
Contract With Customer Liability Additions
Deferred revenue, Additions
Service Based Awards [Member]
Service based awards.
Service Based Awards [Member]
Deferred Tax Assets, Operating Loss Carryforwards
Tax loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Entity Public Float
Entity Public Float
Weighted-average discount rate.
Weighted Average Discount Rate [Abstract]
Weighted-average discount rate
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Kevin Tan [Member]
Kevin Tan.
Kevin Tan [Member]
Percentage of net income and net losses on net sales.
Percentage Of Net Income And Net Losses On Net Sales
Percentage of net income and net losses on net sales
Employee Stock [Member]
Shares Subject to Employee Stock Purchase Plan [Member]
Entity Registrant Name
Entity Registrant Name
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Loss
Restructuring Costs [Abstract]
Entity Voluntary Filers
Entity Voluntary Filers
Other income (expense)
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Other income, net
Subsequent Events [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Agreement termination notice period.
Agreement Termination Notice Period
Agreement termination notice period
Deposit Assets
Restricted cash deposit
Deposit Assets, Total
Income Tax Expense (Benefit)
Income tax expense (benefit)
Total
Asset Acquisition, Assumed Regulatory Milestone Payments
Asset acquisition, assumed regulatory milestone payments.
Assumed regulatory milestone payments
Milestone Liability Payment
Milestone liability payment.
Milestone liability payment
Proceeds from issuance of common stock, net of issuance costs
Proceeds from issuance of common stock
Proceeds from issuance of common stock in public offering, net of sales commissions
Cumulative developmental, regulatory, and commercial milestone payments
Cumulative Developmental, Regulatory, and Commercial Milestone Payments
Cumulative developmental, regulatory, and commercial milestone payments.
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 2.
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level 2
Fair value, assets, transfers out of level 2, amount
Non Cash Collaboration And License Fees
Non-cash collaboration and license fees.
Non-cash collaboration and license fees
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk and of Significant Suppliers
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income
Consolidation Items [Axis]
Commitments and Contingencies, Policy [Policy Text Block]
Contingencies
Payments for Restructuring
Amounts paid during the period
Restructuring charges paid
Restructuring charges were paid
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Assets
Total assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable at December 31, 2025
Income Statement [Abstract]
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]
Restructuring Cost [Table]
Finance Lease, Interest Payment on Liability
Operating cash flows for finance leases
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value Measurements
At-the-Market Offering Sales Agreement [Member]
At-the-Market Offering Sales Agreement [Member]
At-the-market offering sales agreement member.
Share-Based Payment Arrangement [Policy Text Block]
Equity-Based Compensation
Percentage of outstanding common stock.
Percentage Of Outstanding Common Stock
Percentage of outstanding common stock
Average [Member]
Weighted Average [Member]
March 2026 Private Placement [Member]
March 2026 Private Placement.
Development Milestone Payable
Development milestone payable .
Development milestone payable
Income Taxes [Line Items]
Income Taxes [Line Items]
Income Taxes [Line Items]
Stock Issued During Period, Shares, New Issues
Common stock shares issued
Issuance of common stock, net of issuance costs, units
Lease, Cost [Abstract]
Lease costs
Restricted common shares vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
Releases
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share, diluted
Operating segment [Member]
Operating Segments [Member]
Depreciation and amortization expense
Depreciation and amortization excluding impairment loss
Depreciation and amortization excluding impairment loss.
Asset Acquisition [Axis]
External Research And Development Expense S G T 501 [Member]
External research and development expense SGT-501.
External R&D expense - SGT-501 [Member]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
City Area Code
City Area Code
Operating and financing leases.
Operating And Financing Leases Disclosure [Text Block]
Leases
Vesting of restricted stock units.
Vesting Of Restricted Stock Units
Vesting of restricted stock units, units
Auditor Name
Auditor Name
Finance Lease, Liability, Noncurrent
Finance lease obligations, net of current portion
External General And Administrative Expense Executive [Member]
External general and administrative expense executive.
External G&A Expense - Executive [Member]
Income Tax Examination, Penalties and Interest Expense
Tax interest and penalties
Income Tax Examination, Penalties and Interest Expense, Total
Intangible Assets, Finite-Lived, Policy [Policy Text Block]
Patent Costs
One Time Upfront Payment In Cash
One time upfront payment in cash.
One-time upfront payment in cash
Cumulative Regulatory Milestones
Cumulative regulatory milestones.
Cumulative regulatory milestones
Restructuring costs table.
Restructuring Costs [Table]
Restructuring Costs [Table]
Deferred Tax Assets, Tax Credit Carryforwards
Tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Total
Counterparty Name [Domain]
Counterparty Name
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Federal R&D credit
Treasury bill.
Treasury Bill [Member]
Treasury Bills [Member]
Treasury Bills Maturing in One Year or Less [Member]
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock under employee stock purchase plan
Operating Lease, Weighted Average Remaining Lease Term
Operating leases
Lease, Cost
Total lease costs
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Derivative Liability, Current
Derivative liabilities
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
University of Florida license agreements.
University Of Florida License Agreements [Member]
University of Florida License Agreements [Member]
Operating Income (Loss)
Loss from operations
Pre-funded warrants.
Pre Funded Warrants [Member]
Pre-Funded Warrants [Member]
Retained Earnings [Member]
Accumulated Deficit [Member]
Cash and Cash Equivalents [Axis]
Total non-current assets
Assets, Noncurrent
Share-Based Payment Arrangement, Noncash Expense
Equity-based compensation expense
Share-Based Payment Arrangement, Noncash Expense, Total
Measurement Input, Price Volatility [Member]
Volatility [Member]
Payments of Stock Issuance Costs
Payments of common stock and pre-funded warrants issuance costs in private placement
Milestone payments upon achievement of net sales milestones.
Milestone Payments Upon Achievement Of Net Sales Milestones
Milestone Payments upon achievement of net sales milestones
Total non-current liabilities
Liabilities, Noncurrent
Tax credit carryforwards, expiration period.
Tax Credit Carryforwards Expiration Period
Tax credit carryforwards, expiration period
Operating Lease, Weighted Average Discount Rate, Percent
Operating leases
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Fair Value, Inputs, Level 1 [Member]
Level 1 [Member]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Lease, Cost [Table Text Block]
Summary of Components of Lease Costs
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle, accounting standards update, adopted
January 2020 Restructuring Plan [Member]
January 2020 Restructuring Plan [Member]
Asset Acquisition [Abstract]
Auditor Location
Auditor Location
November 2022 Workforce Reduction plan.
November 2022 Workforce Reduction plan [Member]
November 2022 Workforce Reduction Plan [Member]
Other income, net:
Nonoperating Income (Expense) [Abstract]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share
Schedule of Antidilutive Securities Excluded from Calculation of Net Loss per Share
Income Tax Jurisdiction [Domain]
Income Tax Authority
Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).
Lessee, Operating Lease, Liability, to be Paid, after Year Four
Thereafter
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities:
Furniture and Fixtures [Member]
Furniture and Fixtures [Member]
Furniture and Office Equipment [Member]
Asset Acquisition [Line Items]
Accretion (Amortization) of Discounts and Premiums, Investments
Amortization of discount on available-for-sale securities
S G T 501 [Member]
SGT-501.
SGT-501 [Member]
Maximum milestone payment to be made.
Maximum Milestone Payment To Be Made
Maximum milestone payment to be made
Cash Equivalents, at Carrying Value
Cash Equivalents, at Carrying Value, Total
Total cash equivalents
Components of Deferred Tax Liabilities [Abstract]
Deferred tax liabilities:
Entity Tax Identification Number
Entity Tax Identification Number
Warrants Issued
Warrants issued.
Warrants issued
Local Phone Number
Local Phone Number
Accounts receivable related parties additions.
Accounts Receivable Related Parties Additions
Related party collaboration receivable, Additions
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Commitment And Contingencies [Line Items]
Proceeds from Issuance of Common Stock and Pre-funded Warrants in Private Placement
Proceeds from issuance of common stock and pre-funded warrants in private placement.
Proceeds from issuance of common stock and pre-funded warrants in private placement
Auditor Opinion [Text Block]
Milestone payments upon achievement of development milestone.
Milestone Payments Upon Achievement Of Development Milestone
Milestone payments upon achievement of development milestone
Finance Lease, Liability, to be Paid, Year Two
2027
Milestone payment upon achievement of certain milestones.
Milestone Payment Upon Achievement Of Certain Milestones
Milestone payment upon achievement of certain milestones
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Issuance costs
Office Space [Member]
Office Space [Member]
Office space.
Accounting Policies [Abstract]
Income Tax Reconciliation Federal Orphan Drug Credit Amount
Income tax reconciliation federal orphan drug credit amount.
Federal orphan drug credit
Federal orphan drug credit
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Schedule Of Earnings Per Share Basic By Common Class [Table]
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Issuance of common stock in private placement for upfront consideration
Issuance of common stock in private placement for upfront consideration.
Issuance of common stock in private placement for upfront consideration, units
Internal Research And Development Expense [Member]
Internal research and development expense.
Internal Research and Development Expense [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Number of shares available for future issuance
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized equity-based compensation cost, weighted average period
Cash, Cash Equivalents, and Short-Term Investments
Cash, cash equivalents and available-for-sale securities
Cash, Cash Equivalents, and Short-Term Investments, Total
Entity Emerging Growth Company
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest as of December 31, 2025
Indefinite-Lived Intangible Assets [Axis]
Indefinite-lived Intangible Assets